If you’re on the hunt for a comforting, crowd-pleasing dinner that practically guarantees empty plates, look no further than Chicken Bubble Biscuit Bake Casserole. This dish brings together juicy chicken, pillowy biscuits, and a blanket of creamy, cheesy sauce, all baked to bubbly, golden perfection. Picture everything you love about a cozy chicken bake, but with the fun twist of buttery biscuits mingling in every bite—so good you’ll want to make it a regular in your rotation!

Ingredients You’ll Need
Making Chicken Bubble Biscuit Bake Casserole couldn’t be easier, and that’s all thanks to this lineup of straightforward, reassuring ingredients. Every single one plays a starring role in the final flavor and texture, so grab them all for a seriously satisfying meal.
- Cooked chicken: Rotisserie or leftover chicken makes this recipe fast and infuses each bite with hearty protein.
- Cream of chicken soup: The secret to silky, savory sauce that ties the whole bake together—don’t skip it!
- Sour cream: Adds a lovely tang and even more creaminess that balances the richness.
- Milk: Helps create the perfect saucy consistency, ensuring everything bakes up luscious, not dry.
- Garlic powder: Brings a gentle warmth that perks up the creamy base.
- Onion powder: Adds subtle depth and a touch of classic casserole flavor.
- Black pepper: Just enough kick to keep things from getting too mild—essential for rounded taste.
- Shredded cheddar cheese: Melty, gooey, and golden on top; don’t be shy with this crowd-pleaser!
- Refrigerated biscuit dough: Each biscuit gets quartered so you get plenty of fluffy, buttery bites throughout.
- Chopped fresh parsley (optional): For a pop of green and a fresh finish at serving time.
How to Make Chicken Bubble Biscuit Bake Casserole
Step 1: Prep Your Baking Dish and Oven
Start by preheating your oven to 350°F (175°C). While that’s warming up, give a 9×13-inch baking dish a light mist of nonstick spray or a swipe of oil. You’ll be grateful when the casserole slips out in perfect squares later!
Step 2: Mix Up the Creamy Chicken Base
In a large mixing bowl, add your cooked chicken, cream of chicken soup, sour cream, milk, garlic powder, onion powder, black pepper, and one cup of cheddar cheese. Get in there and stir until everything looks creamy and dreamy. This mixture promises every bite of Chicken Bubble Biscuit Bake Casserole has that signature cozy flavor.
Step 3: Add the Biscuit Pieces
Take your refrigerated biscuit dough and cut each biscuit into four little chunks for maximum biscuit bliss throughout the casserole. Drop the biscuit pieces into the cheesy chicken mixture and gently fold everything together until the pieces are well-coated—but be gentle so the biscuits don’t get squished.
Step 4: Assemble and Top With Cheese
Spoon the whole delicious mess into your greased baking dish, spreading it evenly. Sprinkle the remaining half-cup of cheddar cheese over the top for that irresistible golden crust once it bakes—this final layer is what makes the Chicken Bubble Biscuit Bake Casserole truly shine.
Step 5: Bake to Bubbling Perfection
Slide the dish into your preheated oven and bake for 35 to 40 minutes. You’re looking for those biscuit bites to puff up and turn a rich golden brown, with cheese bubbling on top. Let it cool for a few minutes after baking so everyone can dive in without burning their tongues!
How to Serve Chicken Bubble Biscuit Bake Casserole

Garnishes
A sprinkle of fresh chopped parsley takes this hearty casserole from homey to eye-catching in seconds. You could also try finely sliced green onions or a dash of paprika for extra color and fresh flavor that cuts through the creamy richness.
Side Dishes
The beauty of Chicken Bubble Biscuit Bake Casserole is how well it pairs with a crisp, simple salad, steamed green beans, or roasted broccoli. Balance out all that creamy, cheesy goodness with something green for a meal that feels complete without extra fuss.
Creative Ways to Present
For fun, serve the casserole in individual ramekins for dinner-party flair or pack into thermoses for a warm picnic treat. Top each serving with a fried or poached egg for a decadent brunch twist—everyone will want to know your secret!
Make Ahead and Storage
Storing Leftovers
Cool your Chicken Bubble Biscuit Bake Casserole at room temperature before transferring leftovers to an airtight container. They’ll keep happily in the fridge for up to 3 days, and the flavors get even better as they mingle overnight!
Freezing
This casserole is a freezer’s best friend. Cool completely, wrap tightly in foil or plastic wrap, and stash in the freezer for up to 2 months. For individual portions, scoop into freezer-safe bags or containers—the perfect ready-made comfort meal.
Reheating
To reheat, pop leftovers in a 350°F oven, covered, for 20–25 minutes or until hot. For a quicker fix, use the microwave, but add a splash of milk to keep everything moist and fluffy. If frozen, let it thaw overnight in the fridge before reheating for best results.
FAQs
Can I use a different type Main Course
Absolutely! Try Monterey Jack, mozzarella, or a blend for a new twist. Sharp cheddar adds classic flavor, but this casserole is flexible—use your family’s favorite or whatever you have on hand.
How can I make this recipe a bit healthier?
You can use reduced-fat sour cream, low-sodium soup, and part-skim cheese. Adding steamed vegetables like broccoli or peas boosts the nutrition and keeps dinner colorful and balanced.
Do I need to cook the biscuits before adding them to the casserole?
No pre-cooking needed! The biscuit dough bakes right in the creamy mixture, absorbing delicious flavor and turning golden as it cooks. Just be sure to cut the biscuits into small pieces for even baking.
Can I assemble Chicken Bubble Biscuit Bake Casserole ahead of time?
Yes, simply assemble the casserole, cover tightly, and store in the fridge for up to 24 hours before baking. Let it sit at room temperature while the oven preheats, then bake as directed for a fuss-free weeknight dinner.
What’s the best way to check that the biscuits are done?
Look for biscuits that are puffed and golden on top, and insert a toothpick or knife into the center. If it comes out clean (no doughy bits), your Chicken Bubble Biscuit Bake Casserole is ready to enjoy!
Final Thoughts
Once you try Chicken Bubble Biscuit Bake Casserole, you’ll see why it’s loved by families everywhere. It’s creamy, cheesy, and packed with cozy flavor—plus, it comes together with minimal effort. Give it a go and watch it become an instant favorite at your dinner table!
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Chicken Bubble Biscuit Bake Casserole Recipe
- Prep Time: 15 minutes
- Cook Time: 35 minutes
- Total Time: 50 minutes
- Yield: 6 servings
- Category: Main Course
- Method: Baking
- Cuisine: American
- Diet: Non-Vegetarian
Description
This Chicken Bubble Biscuit Bake Casserole is a comforting and easy-to-make dish that the whole family will love. Creamy and flavorful, with tender chicken and fluffy biscuits, it’s perfect for a weeknight dinner or a cozy weekend meal.
Ingredients
Chicken Mixture:
- 2 cups cooked chicken, shredded or cubed
- 1 can (10.5 oz) cream of chicken soup
- 1/2 cup sour cream
- 1/2 cup milk
- 1/2 teaspoon garlic powder
- 1/2 teaspoon onion powder
- 1/4 teaspoon black pepper
- 1 1/2 cups shredded cheddar cheese, divided
Biscuit Topping:
- 1 can (16.3 oz) refrigerated biscuit dough, each biscuit cut into quarters
- 2 tablespoons chopped fresh parsley (optional, for garnish)
Instructions
- Preheat Oven: Preheat the oven to 350°F (175°C) and lightly grease a 9×13-inch baking dish.
- Mix Chicken Mixture: In a large mixing bowl, combine the cooked chicken, cream of chicken soup, sour cream, milk, garlic powder, onion powder, black pepper, and 1 cup of the shredded cheddar cheese. Stir until well mixed.
- Add Biscuits: Gently fold in the biscuit pieces until fully coated with the mixture. Pour everything into the prepared baking dish and spread evenly.
- Add Cheese: Sprinkle the remaining 1/2 cup of cheddar cheese over the top.
- Bake: Bake for 35–40 minutes, or until the biscuits are golden brown and cooked through.
- Serve: Let cool slightly before serving. Garnish with chopped parsley if desired.
Notes
- You can use rotisserie chicken for convenience.
- Add cooked vegetables like peas or broccoli for extra nutrition.
- Substitute cream of mushroom soup for a different flavor.
Nutrition
- Serving Size: 1 portion
- Calories: 430
- Sugar: 3g
- Sodium: 970mg
- Fat: 25g
- Saturated Fat: 11g
- Unsaturated Fat: 11g
- Trans Fat: 0.5g
- Carbohydrates: 30g
- Fiber: 1g
- Protein: 22g
- Cholesterol: 70mg